Ozone generators are a great invention. They charge oxygen molecules, which makes them highly reactive. DC 911 of Orlando gives a lot of guidelines on using one, including the safety methods and procedures on using it. The thing is, ozone is dangerous for living things. That includes humans and pets.
Ozone is especially dangerous to birds, considering it can kill them pretty quickly. You never want anyone to be around the ozone generator when you have it on, including yourself. However, it will kill any microbe like bacteria and viruses as well. This includes odor-causing bacteria and other scent particles like smoke from cigarettes.
In order to remove smoke smells from a room, all you have to do is seal up the room and place the ozone generator in it. After turning it on, quickly leave the room and let it go for about 3-6 hours. It should have a timer so it can shut off automatically. However, if it doesn’t, you’ll have to go in and turn it off yourself.
Running an extension cord out of the room is a good idea, but if you have to go in, be sure to hold your breath. Turn off the ozone generator and exit the room. Letting it sit for about 1-2 hours will allow the ozone to deteriorate and become regular, breathable oxygen again.